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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1948 1
1949 1
1953 2
1958 1
1960 2
1961 2
1962 1
1963 1
1964 1
1965 1
1966 1
1967 3
1968 2
1969 1
1970 3
1971 2
1972 4
1973 7
1974 4
1975 29
1976 32
1977 23
1978 36
1979 39
1980 42
1981 48
1982 49
1983 67
1984 73
1985 81
1986 98
1987 135
1988 127
1989 203
1990 206
1991 236
1992 275
1993 292
1994 315
1995 365
1996 398
1997 423
1998 454
1999 455
2000 528
2001 515
2002 544
2003 610
2004 673
2005 775
2006 817
2007 909
2008 1009
2009 1082
2010 1137
2011 1286
2012 1502
2013 1571
2014 1674
2015 1818
2016 1822
2017 1806
2018 1855
2019 2040
2020 2204
2021 2388
2022 2390
2023 2092
2024 724

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33,802 results

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Page 1
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fuj… See abstract for full author list ➔ Ota T, et al. Nat Genet. 2004 Jan;36(1):40-5. doi: 10.1038/ng1285. Epub 2003 Dec 21. Nat Genet. 2004. PMID: 14702039
The rest of the cDNAs unique to the FLJ collection (5,481) contained no obvious open reading frames (ORFs) and thus are candidate noncoding RNAs. About one-fourth of them (1,378) showed a clear pattern of splicing. ...
The rest of the cDNAs unique to the FLJ collection (5,481) contained no obvious open reading frames (ORFs) and thus are candid …
Nudging accurate scientific communication.
Allard A, Clavien C. Allard A, et al. PLoS One. 2023 Aug 31;18(8):e0290225. doi: 10.1371/journal.pone.0290225. eCollection 2023. PLoS One. 2023. PMID: 37651386 Free PMC article.
In order to steer participants' choices towards or against the trustworthy transmission of science, we used several soft framing nudges and social incentives. Overall, we find that, although participants show a strong preference for studies using high-sample sizes and rand …
In order to steer participants' choices towards or against the trustworthy transmission of science, we used several soft framing nudg …
Molecular and functional characterization of the Drosophila melanogaster conserved smORFome.
Bosch JA, Keith N, Escobedo F, Fisher WW, LaGraff JT, Rabasco J, Wan KH, Weiszmann R, Hu Y, Kondo S, Brown JB, Perrimon N, Celniker SE. Bosch JA, et al. Cell Rep. 2023 Nov 28;42(11):113311. doi: 10.1016/j.celrep.2023.113311. Epub 2023 Oct 26. Cell Rep. 2023. PMID: 37889754 Free PMC article.
Short polypeptides encoded by small open reading frames (smORFs) are ubiquitously found in eukaryotic genomes and are important regulators of physiology, development, and mitochondrial processes. ...We observe remarkably heterogeneous spatial and temporal expression …
Short polypeptides encoded by small open reading frames (smORFs) are ubiquitously found in eukaryotic genomes and are importan …
Hundreds of Out-of-Frame Remodeled Gene Families in the Escherichia coli Pangenome.
Watson AK, Lopez P, Bapteste E. Watson AK, et al. Mol Biol Evol. 2022 Jan 7;39(1):msab329. doi: 10.1093/molbev/msab329. Mol Biol Evol. 2022. PMID: 34792602 Free PMC article.
A special case of de novo gene formation, overprinting, describes the origin of new genes from noncoding alternative reading frames of existing open reading frames (ORFs). We argue that additionally, out-of-frame gene fission/fusion events of al …
A special case of de novo gene formation, overprinting, describes the origin of new genes from noncoding alternative reading frame …
The fragmented gene.
Brosius J. Brosius J. Ann N Y Acad Sci. 2009 Oct;1178:186-93. doi: 10.1111/j.1749-6632.2009.05004.x. Ann N Y Acad Sci. 2009. PMID: 19845638 Review.
While once almost synonymous, there is an increasing gap between the expanding definition of what constitutes a gene and the conservative and narrowly defined terms code or coding, which for a long time, almost exclusively constituted the open reading frame. Much co …
While once almost synonymous, there is an increasing gap between the expanding definition of what constitutes a gene and the conservative an …
Functional properties and sequence variation of HTLV-1 p13.
Omsland M, Silic-Benussi M, Moles R, Sarkis S, Purcell DFJ, Yurick D, Khoury G, D'Agostino DM, Ciminale V, Franchini G. Omsland M, et al. Retrovirology. 2020 May 12;17(1):11. doi: 10.1186/s12977-020-00517-1. Retrovirology. 2020. PMID: 32398094 Free PMC article. Review.
This review describes the functional properties of p13, an 87-amino acid protein coded by HTLV-1 open reading frame II (orf-II). p13 is mainly localized in the inner membrane of the mitochondria, where it induces potassium (K(+)) influx and reactive oxygen species ( …
This review describes the functional properties of p13, an 87-amino acid protein coded by HTLV-1 open reading frame II (orf-II …
Inferring the effect of genomic variation in the new era of genomics.
Chakravorty S, Hegde M. Chakravorty S, et al. Hum Mutat. 2018 Jun;39(6):756-773. doi: 10.1002/humu.23427. Epub 2018 Apr 22. Hum Mutat. 2018. PMID: 29633501 Review.
In this review, we describe the trends in research at the intersection of basic and clinical genomics aiming to (a) overcome molecular diagnostic challenges and increase the clinical utility of next-generation sequencing (NGS) platforms, (b) elucidate variants associated with dis …
In this review, we describe the trends in research at the intersection of basic and clinical genomics aiming to (a) overcome molecular diagn …
Combinatorial pathway optimization for streamlined metabolic engineering.
Jeschek M, Gerngross D, Panke S. Jeschek M, et al. Curr Opin Biotechnol. 2017 Oct;47:142-151. doi: 10.1016/j.copbio.2017.06.014. Epub 2017 Aug 17. Curr Opin Biotechnol. 2017. PMID: 28750202 Review.
However, due to the high complexity of cellular metabolism, the limited a priori knowledge about the majority of production pathways and a lack of forward design standards, metabolic engineers strongly rely on empirical screening methodologies to achieve the required improvement …
However, due to the high complexity of cellular metabolism, the limited a priori knowledge about the majority of production pathways and a l …
Triple Intergenotype Recombination of Human Astrovirus 5, Human Astrovirus 8, and Human Astrovirus 1 in the Open Reading Frame 1a, Open Reading Frame 1b, and Open Reading Frame 2 Regions of the Human Astrovirus Genome.
Wei H, Kumthip K, Khamrin P, Yodmeeklin A, Jampanil N, Phengma P, Xie Z, Ukarapol N, Ushijima H, Maneekarn N. Wei H, et al. Microbiol Spectr. 2023 Jun 15;11(3):e0488822. doi: 10.1128/spectrum.04888-22. Epub 2023 Apr 5. Microbiol Spectr. 2023. PMID: 37017548 Free PMC article.
Human astrovirus (HAstV) strains exhibit high levels of genetic diversity, and many recombinant strains with different recombination patterns have been reported. The aims of the present study were to investigate the emergence of HAstV recombinant strains and to characteriz …
Human astrovirus (HAstV) strains exhibit high levels of genetic diversity, and many recombinant strains with different recombination patt …
Regulation of plant translation by upstream open reading frames.
von Arnim AG, Jia Q, Vaughn JN. von Arnim AG, et al. Plant Sci. 2014 Jan;214:1-12. doi: 10.1016/j.plantsci.2013.09.006. Epub 2013 Sep 18. Plant Sci. 2014. PMID: 24268158 Review.
We review the evidence that upstream open reading frames (uORFs) function as RNA sequence elements for post-transcriptional control of gene expression, specifically translation. uORFs are highly abundant in the genomes of angiosperms. ...While many uORFs appear to b …
We review the evidence that upstream open reading frames (uORFs) function as RNA sequence elements for post-transcriptional co …
33,802 results
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